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Mechanisms of Blindness: Animal Models Provide Insight into Distinct CRX-Associated Retinopathies
The homeodomain transcription factor CRX is a crucial regulator of mammalian photoreceptor gene expression. Mutations in the human CRX gene are associated with dominant inherited retinopathies Retinitis Pigmentosa (RP), Cone-Rod Dystrophy (CoRD) and Leber Congenital Amaurosis (LCA), of varying sever...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4177283/ https://ncbi.nlm.nih.gov/pubmed/24888636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24151 |
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