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Crx(Rdy) Cat: A Large Animal Model for CRX-Associated Leber Congenital Amaurosis
PURPOSE: Mutations in the retinal transcription factor cone-rod homeobox (CRX) gene result in severe dominant retinopathies. A large animal model, the Rdy cat, carrying a spontaneous frameshift mutation in Crx, was reported previously. The present study aimed to further understand pathogenesis in th...
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| Publié dans: | Invest Ophthalmol Vis Sci |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Association for Research in Vision and Ophthalmology
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960999/ https://ncbi.nlm.nih.gov/pubmed/27427859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19444 |
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