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Mechanisms of Blindness: Animal Models Provide Insight into Distinct CRX-Associated Retinopathies

The homeodomain transcription factor CRX is a crucial regulator of mammalian photoreceptor gene expression. Mutations in the human CRX gene are associated with dominant inherited retinopathies Retinitis Pigmentosa (RP), Cone-Rod Dystrophy (CoRD) and Leber Congenital Amaurosis (LCA), of varying sever...

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Hlavní autoři: Tran, Nicholas M., Chen, Shiming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177283/
https://ncbi.nlm.nih.gov/pubmed/24888636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.24151
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