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Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif

Small interfering RNAs (siRNAs) are widely used to repress gene expression by targeting mRNAs. Some reports reveal that siRNAs can also activate or inhibit gene expression through targeting the gene promoters. Our group has found that microRNAs (miRNAs) could activate gene transcription via interact...

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Detalles Bibliográficos
Main Authors: Fan, Miaomiao, Zhang, Yijun, Huang, Zhuoqiong, Liu, Jun, Guo, Xuemin, Zhang, Hui, Luo, Haihua
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176967/
https://ncbi.nlm.nih.gov/pubmed/25250958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108253
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