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Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif
Small interfering RNAs (siRNAs) are widely used to repress gene expression by targeting mRNAs. Some reports reveal that siRNAs can also activate or inhibit gene expression through targeting the gene promoters. Our group has found that microRNAs (miRNAs) could activate gene transcription via interact...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176967/ https://ncbi.nlm.nih.gov/pubmed/25250958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108253 |
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