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Optimizations of SiRNA Design for the Activation of Gene Transcription by Targeting the TATA-Box Motif
Small interfering RNAs (siRNAs) are widely used to repress gene expression by targeting mRNAs. Some reports reveal that siRNAs can also activate or inhibit gene expression through targeting the gene promoters. Our group has found that microRNAs (miRNAs) could activate gene transcription via interact...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176967/ https://ncbi.nlm.nih.gov/pubmed/25250958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108253 |
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