Synthesis, properties, and biological activity of boranophosphate analogs of the mRNA cap: versatile tools for manipulation of therapeutically relevant cap-dependent processes

Modified mRNA cap analogs aid in the study of mRNA-related processes and may enable creation of novel therapeutic interventions. We report the synthesis and properties of 11 dinucleotide cap analogs bearing a single boranophosphate modification at either the α-, β- or γ-position of the 5′,5′-triphos...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kowalska, Joanna, Wypijewska del Nogal, Anna, Darzynkiewicz, Zbigniew M., Buck, Janina, Nicola, Corina, Kuhn, Andreas N., Lukaszewicz, Maciej, Zuberek, Joanna, Strenkowska, Malwina, Ziemniak, Marcin, Maciejczyk, Maciej, Bojarska, Elzbieta, Rhoads, Robert E., Darzynkiewicz, Edward, Sahin, Ugur, Jemielity, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Synthetic Biology and Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176373/
https://ncbi.nlm.nih.gov/pubmed/25150148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku757
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados