Arrestin-dependent Angiotensin AT(1) Receptor Signaling Regulates Akt and mTor-mediated Protein Synthesis

Control of protein synthesis is critical to both cell growth and proliferation. The mammalian target of rapamycin (mTOR) integrates upstream growth, proliferation, and survival signals, including those transmitted via ERK1/2 and Akt, to regulate the rate of protein translation. The angiotensin AT(1)...

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Main Authors: Kendall, Ryan T., Lee, Mi-Hye, Pleasant, Dorea L., Robinson, Katherine, Kuppuswamy, Dhandapani, McDermott, Paul J., Luttrell, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176252/
https://ncbi.nlm.nih.gov/pubmed/25081544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595728
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