Binding Induced RNA Conformational Changes Control Substrate Recognition and Catalysis by the Thiostrepton Resistance Methyltransferase (Tsr)

Ribosomal RNA (rRNA) post-transcriptional modifications are essential for ribosome maturation, translational fidelity, and are one mechanism used by both antibiotic-producing and pathogenic bacteria to resist the effects of antibiotics that target the ribosome. The thiostrepton producer Streptomyces...

Full description

Saved in:
Bibliographic Details
Main Authors: Kuiper, Emily G., Conn, Graeme L.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176221/
https://ncbi.nlm.nih.gov/pubmed/25086036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.574780
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items