DNA2 Cooperates with the WRN and BLM RecQ Helicases to Mediate Long-range DNA End Resection in Human Cells

The 5′-3′ resection of DNA ends is a prerequisite for the repair of DNA double strand breaks by homologous recombination, microhomology-mediated end joining, and single strand annealing. Recent studies in yeast have shown that, following initial DNA end processing by the Mre11-Rad50-Xrs2 complex and...

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Библиографические подробности
Главные авторы: Sturzenegger, Andreas, Burdova, Kamila, Kanagaraj, Radhakrishnan, Levikova, Maryna, Pinto, Cosimo, Cejka, Petr, Janscak, Pavel
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
DNA and Chromosomes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175362/
https://ncbi.nlm.nih.gov/pubmed/25122754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578823
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