The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation

BACKGROUND: The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood. METHODS:...

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Hlavní autoři: Sandén, Carl, Järvstråt, Linnea, Lennartsson, Andreas, Brattås, Per Ludvik, Nilsson, Björn, Gullberg, Urban
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175287/
https://ncbi.nlm.nih.gov/pubmed/25216995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-215
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