The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation

BACKGROUND: The DEK gene is highly expressed in a wide range of cancer cells, and a recurrent translocation partner in acute myeloid leukemia. While DEK has been identified as one of the most abundant proteins in human chromatin, its function and binding properties are not fully understood. METHODS:...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sandén, Carl, Järvstråt, Linnea, Lennartsson, Andreas, Brattås, Per Ludvik, Nilsson, Björn, Gullberg, Urban
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4175287/
https://ncbi.nlm.nih.gov/pubmed/25216995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-215
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