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Intercellular trafficking of the nuclear oncoprotein DEK
DEK is a biochemically distinct, conserved nonhistone protein that is vital to global heterochromatin integrity. In addition, DEK can be secreted and function as a chemotactic, proinflammatory factor. Here we show that exogenous DEK can penetrate cells, translocate to the nucleus, and there carry ou...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637753/ https://ncbi.nlm.nih.gov/pubmed/23569252 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220751110 |
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