A Defined Zebrafish Line for High-Throughput Genetics and Genomics: NHGRI-1

Substantial intrastrain variation at the nucleotide level complicates molecular and genetic studies in zebrafish, such as the use of CRISPRs or morpholinos to inactivate genes. In the absence of robust inbred zebrafish lines, we generated NHGRI-1, a healthy and fecund strain derived from founder par...

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Main Authors: LaFave, Matthew C., Varshney, Gaurav K., Vemulapalli, Meghana, Mullikin, James C., Burgess, Shawn M.
格式: Artigo
語言:Inglês
出版: Genetics Society of America 2014
主題:
Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174928/
https://ncbi.nlm.nih.gov/pubmed/25009150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.166769
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