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A Defined Zebrafish Line for High-Throughput Genetics and Genomics: NHGRI-1

Substantial intrastrain variation at the nucleotide level complicates molecular and genetic studies in zebrafish, such as the use of CRISPRs or morpholinos to inactivate genes. In the absence of robust inbred zebrafish lines, we generated NHGRI-1, a healthy and fecund strain derived from founder par...

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Hlavní autoři: LaFave, Matthew C., Varshney, Gaurav K., Vemulapalli, Meghana, Mullikin, James C., Burgess, Shawn M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174928/
https://ncbi.nlm.nih.gov/pubmed/25009150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.166769
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