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The Notch Ligand Jagged1 as a Target for Anti-Tumor Therapy

The Notch pathway is increasingly attracting attention as a source of therapeutic targets for cancer. Ligand-induced Notch signaling has been implicated in various aspects of cancer biology; as a consequence, pan-Notch inhibitors and therapeutic antibodies targeting one or more of the Notch receptor...

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Hlavní autoři: Li, Demin, Masiero, Massimo, Banham, Alison H., Harris, Adrian L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174884/
https://ncbi.nlm.nih.gov/pubmed/25309874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00254
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