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Distinct Biological Roles for the Notch Ligands Jagged-1 and Jagged-2

Notch signaling is activated in a subset of non-small cell lung cancer cells because of overexpression of Notch3, but the role of Notch ligands has not been fully defined. On the basis of gene expression profiling of a panel of non-small cell lung cancer cell lines, we found that the predominant Not...

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Bibliographic Details
Main Authors: Choi, Kuicheon, Ahn, Young-Ho, Gibbons, Don L., Tran, Hai T., Creighton, Chad J., Girard, Luc, Minna, John D., Qin, F. Xiao-Feng, Kurie, Jonathan M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719415/
https://ncbi.nlm.nih.gov/pubmed/19398556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003111
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