NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma

Medulloblastoma (MB), the most common pediatric malignant brain cancer, typically arises as pathological result of deregulated developmental pathways, including the NOTCH signaling cascade. Unlike the evidence supporting a role for NOTCH receptors in MB development, the pathological functions of NOT...

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Detalhes bibliográficos
Main Authors: Fiaschetti, Giulio, Schroeder, Christina, Castelletti, Deborah, Arcaro, Alexandre, Westermann, Frank, Baumgartner, Martin, Shalaby, Tarek, Grotzer, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023630/
https://ncbi.nlm.nih.gov/pubmed/24708907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-39
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