Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells

BACKGROUND: With current treatment strategies, nearly half of all medulloblastoma (MB) patients die from progressive tumors. Accordingly, the identification of novel therapeutic strategies remains a major goal. Deregulation of c-MYC is evident in numerous human cancers. In MB, over-expression of c-M...

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Autori principali: von Bueren, André O, Shalaby, Tarek, Rajtarova, Julia, Stearns, Duncan, Eberhart, Charles G, Helson, Lawrence, Arcaro, Alexandre, Grotzer, Michael A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794252/
https://ncbi.nlm.nih.gov/pubmed/17254356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-19
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