c-MYC expression sensitizes medulloblastoma cells to radio- and chemotherapy and has no impact on response in medulloblastoma patients

BACKGROUND: To study whether and how c-MYC expression determines response to radio- and chemotherapy in childhood medulloblastoma (MB). METHODS: We used DAOY and UW228 human MB cells engineered to stably express different levels of c-MYC, and tested whether c-MYC expression has an effect on radio- a...

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Detalhes bibliográficos
Main Authors: von Bueren, André O, Oehler, Christoph, Shalaby, Tarek, von Hoff, Katja, Pruschy, Martin, Seifert, Burkhardt, Gerber, Nicolas U, Warmuth-Metz, Monika, Stearns, Duncan, Eberhart, Charles G, Kortmann, Rolf D, Rutkowski, Stefan, Grotzer, Michael A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050852/
https://ncbi.nlm.nih.gov/pubmed/21324178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-74
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