Determinant roles of dendritic cell-expressed Notch Delta-like and Jagged ligands on anti-tumor T cell immunity

BACKGROUND: Notch intercellular communication instructs tissue-specific T-cell development and function. In this study, we explored the roles of dendritic cell (DC)-expressed Notch ligands in the regulation of T-cell effector function. METHODS: We generated mice with CD11c lineage-specific deletion...

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Publicado no:J Immunother Cancer
Main Authors: Tchekneva, Elena E., Goruganthu, Mounika U.L., Uzhachenko, Roman V., Thomas, Portia L., Antonucci, Anneliese, Chekneva, Irina, Koenig, Michael, Piao, Longzhu, Akhter, Anwari, de Aquino, Maria Teresa P., Ranganathan, Parvathi, Long, Nicholas, Magliery, Thomas, Valujskikh, Anna, Evans, Jason V., Arasada, Rajeswara R., Massion, Pierre P., Carbone, David P., Shanker, Anil, Dikov, Mikhail M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446314/
https://ncbi.nlm.nih.gov/pubmed/30940183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0566-4
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