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Serum mitochondrial biomarkers and damage-associated molecular patterns are higher in acetaminophen overdose patients with poor outcome
Acetaminophen (APAP) overdose is a major cause of acute liver failure (ALF). Numerous studies have shown that APAP hepatotoxicity in mice involves mitochondrial dysfunction, and recent data suggest this is also the case in humans. We have previously shown that glutamate dehydrogenase (GDH), mitochon...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4174728/ https://ncbi.nlm.nih.gov/pubmed/24923598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27265 |
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