Argininosuccinate synthetase as a plasma biomarker of liver injury after acetaminophen overdose in rodents and humans

CONTEXT: New biomarkers are needed in acetaminophen (APAP) hepatotoxicity. Plasma argininosuccinate synthetase (ASS) is a promising candidate. OBJECTIVE: Characterize ASS in APAP hepatotoxicity. METHODS: ASS was measured in plasma from rodents and humans with APAP hepatotoxicity. RESULTS: In mice, A...

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Detalhes bibliográficos
Publicado no:Biomarkers
Main Authors: McGill, Mitchell R., Cao, Mengde, Svetlov, Archie, Sharpe, Matthew R., Williams, C. David, Curry, Steven C., Farhood, Anwar, Jaeschke, Hartmut, Svetlov, Stanislav I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4280854/
https://ncbi.nlm.nih.gov/pubmed/24597531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1354750X.2014.897757
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