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Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states
The Notch signaling pathway consists of multiple types of receptors and ligands, whose interactions can be tuned by Fringe glycosyltransferases. A major challenge is to determine how these components control the specificity and directionality of Notch signaling in developmental contexts. Here, we an...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4174579/ https://ncbi.nlm.nih.gov/pubmed/25255098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02950 |
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