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Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands

Notch signaling is an evolutionarily conserved cell-cell communication system used broadly in animal development and adult maintenance. Interaction of the Notch receptor with ligands from neighboring cells induces activation of the signaling pathway (trans-activation), while interaction with ligands...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Pandey, Ashutosh, Jafar-Nejad, Hamed
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5875548/
https://ncbi.nlm.nih.gov/pubmed/29364239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/56919
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