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Mutual Inactivation of Notch Receptors and Ligands Facilitates Developmental Patterning

Developmental patterning requires juxtacrine signaling in order to tightly coordinate the fates of neighboring cells. Recent work has shown that Notch and Delta, the canonical metazoan juxtacrine signaling receptor and ligand, mutually inactivate each other in the same cell. This cis-interaction gen...

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Detaylı Bibliyografya
Asıl Yazarlar: Sprinzak, David, Lakhanpal, Amit, LeBon, Lauren, Garcia-Ojalvo, Jordi, Elowitz, Michael B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111533/
https://ncbi.nlm.nih.gov/pubmed/21695234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002069
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