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Critical role of neutral cholesteryl ester hydrolase 1 in cholesteryl ester hydrolysis in murine macrophages

Hydrolysis of intracellular cholesteryl ester (CE) is the rate-limiting step in the efflux of cholesterol from macrophage foam cells. In mouse peritoneal macrophages (MPMs), this process is thought to involve several enzymes: hormone-sensitive lipase (Lipe), carboxylesterase 3 (Ces3), neutral CE hyd...

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Bibliographic Details
Main Authors: Sakai, Kent, Igarashi, Masaki, Yamamuro, Daisuke, Ohshiro, Taichi, Nagashima, Shuichi, Takahashi, Manabu, Enkhtuvshin, Bolormaa, Sekiya, Motohiro, Okazaki, Hiroaki, Osuga, Jun-ichi, Ishibashi, Shun
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4173996/
https://ncbi.nlm.nih.gov/pubmed/24868095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M047787
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