Targeting of neutral cholesterol ester hydrolase to the endoplasmic reticulum via its N-terminal sequence

Neutral cholesterol ester hydrolase (NCEH) accounts for a large part of the nCEH activity in macrophage foam cells, a hallmark of atherosclerosis, but its subcellular localization and structure-function relationship are unknown. Here, we determined subcellular localization, glycosylation, and nCEH a...

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Detalhes bibliográficos
Main Authors: Igarashi, Masaki, Osuga, Jun-ichi, Isshiki, Masashi, Sekiya, Motohiro, Okazaki, Hiroaki, Takase, Satoru, Takanashi, Mikio, Ohta, Keisuke, Kumagai, Masayoshi, Nishi, Makiko, Fujita, Toshiro, Nagai, Ryozo, Kadowaki, Takashi, Ishibashi, Shun
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2803229/
https://ncbi.nlm.nih.gov/pubmed/19592704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M900201-JLR200
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