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Inhibition of phosphodiesterase 5 restores endothelial function in renovascular hypertension
BACKGROUND: The clipping of an artery supplying one of the two kidneys (2K1C) activates the renin-angiotensin (Ang) system (RAS), resulting in hypertension and endothelial dysfunction. Recently, we demonstrated the intrarenal beneficial effects of sildenafil on the high levels of Ang II and reactive...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172908/ https://ncbi.nlm.nih.gov/pubmed/25223948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-014-0250-x |
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