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Sildenafil ameliorates biomarkers of genotoxicity in an experimental model of spontaneous atherosclerosis
BACKGROUND: It is well known that enhanced production of reactive oxygen species (ROS) leads to oxidative stress observed in atherosclerosis and that ROS can also cause damage in cellular macromolecules, including DNA. Considering previous report that sildenafil, an inhibitor of phosphodiesterase 5...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3766097/ https://ncbi.nlm.nih.gov/pubmed/23981672 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-128 |
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