Sildenafil ameliorates biomarkers of genotoxicity in an experimental model of spontaneous atherosclerosis

BACKGROUND: It is well known that enhanced production of reactive oxygen species (ROS) leads to oxidative stress observed in atherosclerosis and that ROS can also cause damage in cellular macromolecules, including DNA. Considering previous report that sildenafil, an inhibitor of phosphodiesterase 5...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Rodrigues, Bianca P, Campagnaro, Bianca P, Balarini, Camille M, Pereira, Thiago M C, Meyrelles, Silvana S, Vasquez, Elisardo C
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2013
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766097/
https://ncbi.nlm.nih.gov/pubmed/23981672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-12-128
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires