Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension

BACKGROUND: Oxidative stress and DNA damage have been implicated in the pathogenesis of renovascular hypertension induced by renal artery stenosis in the two-kidney, one-clip (2K1C) Goldblatt model. Considering our previous report indicating that the chronic blockade of phosphodiesterase 5 with sild...

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Hlavní autoři: Dias, Ananda T, Rodrigues, Bianca P, Porto, Marcella L, Gava, Agata L, Balarini, Camille M, Freitas, Flavia P S, Palomino, Zaira, Casarini, Dulce E, Campagnaro, Bianca P, Pereira, Thiago M C, Meyrelles, Silvana S, Vasquez, Elisardo C
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3922021/
https://ncbi.nlm.nih.gov/pubmed/24502628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-35
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