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Sildenafil restores endothelial function in the apolipoprotein E knockout mouse
BACKGROUND: Atherosclerosis is an inflammatory process of the arterial walls and is initiated by endothelial dysfunction accompanied by an imbalance in the production of reactive oxygen species (ROS) and nitric oxide (NO). Sildenafil, a selective phosphodiesterase-5 (PDE5) inhibitor used for erectil...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3551739/ https://ncbi.nlm.nih.gov/pubmed/23289368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-3 |
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