Sildenafil restores endothelial function in the apolipoprotein E knockout mouse

BACKGROUND: Atherosclerosis is an inflammatory process of the arterial walls and is initiated by endothelial dysfunction accompanied by an imbalance in the production of reactive oxygen species (ROS) and nitric oxide (NO). Sildenafil, a selective phosphodiesterase-5 (PDE5) inhibitor used for erectil...

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Detalhes bibliográficos
Main Authors: Balarini, Camille M, Leal, Marcos A, Gomes, Isabele B S, Pereira, Thiago M C, Gava, Agata L, Meyrelles, Silvana S, Vasquez, Elisardo C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551739/
https://ncbi.nlm.nih.gov/pubmed/23289368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-3
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