Sildenafil restores endothelial function in the apolipoprotein E knockout mouse

BACKGROUND: Atherosclerosis is an inflammatory process of the arterial walls and is initiated by endothelial dysfunction accompanied by an imbalance in the production of reactive oxygen species (ROS) and nitric oxide (NO). Sildenafil, a selective phosphodiesterase-5 (PDE5) inhibitor used for erectil...

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Main Authors: Balarini, Camille M, Leal, Marcos A, Gomes, Isabele B S, Pereira, Thiago M C, Gava, Agata L, Meyrelles, Silvana S, Vasquez, Elisardo C
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551739/
https://ncbi.nlm.nih.gov/pubmed/23289368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-11-3
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