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Enhanced Immunogenicity of HIV-1 Envelope gp140 Proteins Fused to APRIL
Current HIV-1 vaccines based on the HIV-1 envelope glycoprotein spike (Env), the only relevant target for broadly neutralizing antibodies, are unable to induce protective immunity. Env immunogenicity can be enhanced by fusion to costimulatory molecules involved in B cell activation, such as APRIL an...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4172553/ https://ncbi.nlm.nih.gov/pubmed/25247707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107683 |
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