Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal Cancer

Numerous changes in epigenetic mechanisms have been described in various types of tumors. In search for new biomarkers, we investigated the expression of Polycomb-group (PcG) proteins EZH2, BMI1 and SUZ12 and associated histone modification H3K27me3 in colorectal cancer. Nuclear expression of PcG pr...

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Autori principali: Benard, Anne, Goossens-Beumer, Inès J., van Hoesel, Anneke Q., Horati, Hamed, Putter, Hein, Zeestraten, Eliane C. M., van de Velde, Cornelis J. H., Kuppen, Peter J. K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171510/
https://ncbi.nlm.nih.gov/pubmed/25243792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108265
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