The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens

We used SEREX technology to identify novel tumour-associated antigens in patients with primary hepatocellular carcinoma and found serological responses to the polycomb group (PcG) protein BMI-1, which is overexpressed in a range of different tumour types. Further studies identified T-cell responses...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Steele, J C, Torr, E E, Noakes, K L, Kalk, E, Moss, P A, Reynolds, G M, Hubscher, S G, van Lohuizen, M, Adams, D H, Young, L S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2006
Schlagworte:
Translational Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2360579/
https://ncbi.nlm.nih.gov/pubmed/17024127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603369
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