Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcoma

BACKGROUND: Polycomb repressive complex 2 (PRC2; formed by EZH2, SUZ12, and EED protein subunits) and PRC1 (BMI1 protein) induce gene silencing through histone modification by H3K27me3. In the present study, we characterized the PRC expression pattern and its clinical implication in sarcoma. METHODS...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Cho, Yong Jin, Kim, Soo Hee, Kim, Eun Kyung, Han, Jung Woo, Shin, Kyoo-Ho, Hu, Hyuk, Kim, Kyung Sik, Choi, Young Deuk, Kim, Sunghoon, Lee, Young Han, Suh, Jin-Suck, Ahn, Joong Bae, Chung, Hyun Cheol, Noh, Sung Hoon, Rha, Sun Young, Jung, Sung-Taek, Kim, Hyo Song
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804074/
https://ncbi.nlm.nih.gov/pubmed/29415665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4066-6
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