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Targeted Disruption of the EZH2/EED Complex Inhibits EZH2-dependent Cancer
Enhancer of zeste homolog2 (EZH2) is the histone lysine N-methyltransferase component of the Polycomb repressive complex 2 (PRC2), which in conjunction with embryonic ectoderm development (EED) and suppressor of zeste 12 homolog (SUZ12), regulates cell lineage determination and homeostasis. Enzymati...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3778130/ https://ncbi.nlm.nih.gov/pubmed/23974116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1331 |
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