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Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal Cancer

Numerous changes in epigenetic mechanisms have been described in various types of tumors. In search for new biomarkers, we investigated the expression of Polycomb-group (PcG) proteins EZH2, BMI1 and SUZ12 and associated histone modification H3K27me3 in colorectal cancer. Nuclear expression of PcG pr...

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Main Authors: Benard, Anne, Goossens-Beumer, Inès J., van Hoesel, Anneke Q., Horati, Hamed, Putter, Hein, Zeestraten, Eliane C. M., van de Velde, Cornelis J. H., Kuppen, Peter J. K.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171510/
https://ncbi.nlm.nih.gov/pubmed/25243792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108265
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