Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis.

Ítems similars

• Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines.
  per: Li, W, et al.
  Publicat: (1995)
• Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis.
  per: Shan, B, et al.
  Publicat: (1994)
• E2F Is Required To Prevent Inappropriate S-Phase Entry of Mammalian Cells
  per: He, Song, et al.
  Publicat: (2000)
• Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
  per: Qin, X Q, et al.
  Publicat: (1994)
• Inhibition of apoptosis by the retinoblastoma gene product.
  per: Haas-Kogan, D A, et al.
  Publicat: (1995)