Mode of action of the biotin antimetabolites actithiazic acid and alpha-methyldethiobiotin.
Actithiazic acid and alpha-methyldethiobiotin inhibited the conversion of dethiobiotin to biotin resting-cell suspensions of Escherichia coli. The concentrations which effected 50% inhibition were 0.45 and 1.1 microM for actithiazic acid and alpha-methyldethiobiotin, respectively. Cells grown in low...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181820/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7044300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.1.5 |
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