Mode of action of the biotin antimetabolites actithiazic acid and alpha-methyldethiobiotin.

Actithiazic acid and alpha-methyldethiobiotin inhibited the conversion of dethiobiotin to biotin resting-cell suspensions of Escherichia coli. The concentrations which effected 50% inhibition were 0.45 and 1.1 microM for actithiazic acid and alpha-methyldethiobiotin, respectively. Cells grown in low...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Eisenberg, M A, Hsiung, S C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1982
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC181820/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7044300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.21.1.5
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