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Monocyclic and tricyclic analogs of quinolones: mechanism of action.

The mode of action of Ro 13-5478 and Ro 14-9578, monocyclic and tricyclic quinolone analogs, respectively, was examined for Escherichia coli and Staphylococcus aureus. The compounds showed antibacterial activity and effects on cell morphology, replicative DNA biosynthesis, and gyrase-catalyzed DNA s...

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Detalhes bibliográficos
Main Authors: Georgopapadakou, N H, Dix, B A, Angehrn, P, Wick, A, Olson, G L
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC174788/
https://ncbi.nlm.nih.gov/pubmed/3037999
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