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Monocyclic and tricyclic analogs of quinolones: mechanism of action.

The mode of action of Ro 13-5478 and Ro 14-9578, monocyclic and tricyclic quinolone analogs, respectively, was examined for Escherichia coli and Staphylococcus aureus. The compounds showed antibacterial activity and effects on cell morphology, replicative DNA biosynthesis, and gyrase-catalyzed DNA s...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Georgopapadakou, N H, Dix, B A, Angehrn, P, Wick, A, Olson, G L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174788/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037999/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.4.614
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