Monocyclic and tricyclic analogs of quinolones: mechanism of action.

The mode of action of Ro 13-5478 and Ro 14-9578, monocyclic and tricyclic quinolone analogs, respectively, was examined for Escherichia coli and Staphylococcus aureus. The compounds showed antibacterial activity and effects on cell morphology, replicative DNA biosynthesis, and gyrase-catalyzed DNA s...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Principais autores:	Georgopapadakou, N H, Dix, B A, Angehrn, P, Wick, A, Olson, G L
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174788/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.31.4.614
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