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Mendelian randomization: genetic anchors for causal inference in epidemiological studies

Observational epidemiological studies are prone to confounding, reverse causation and various biases and have generated findings that have proved to be unreliable indicators of the causal effects of modifiable exposures on disease outcomes. Mendelian randomization (MR) is a method that utilizes gene...

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Hlavní autoři: Davey Smith, George, Hemani, Gibran
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170722/
https://ncbi.nlm.nih.gov/pubmed/25064373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu328
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