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Mendelian randomization: genetic anchors for causal inference in epidemiological studies

Observational epidemiological studies are prone to confounding, reverse causation and various biases and have generated findings that have proved to be unreliable indicators of the causal effects of modifiable exposures on disease outcomes. Mendelian randomization (MR) is a method that utilizes gene...

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Detalhes bibliográficos
Main Authors: Davey Smith, George, Hemani, Gibran
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170722/
https://ncbi.nlm.nih.gov/pubmed/25064373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu328
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