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Causal inference in cancer epidemiology: what is the role of Mendelian randomization?

Observational epidemiological studies are prone to confounding, measurement error, and reverse causation, undermining robust causal inference. Mendelian randomization (MR) uses genetic variants to proxy modifiable exposures to generate more reliable estimates of the causal effects of these exposures...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Yarmolinsky, James, Wade, Kaitlin H, Richmond, Rebecca C, Langdon, Ryan J, Bull, Caroline J, Tilling, Kate M, Relton, Caroline L, Lewis, Sarah J, Smith, George Davey, Martin, Richard M
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522350/
https://ncbi.nlm.nih.gov/pubmed/29941659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-17-1177
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