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Mendelian randomization: genetic anchors for causal inference in epidemiological studies

Observational epidemiological studies are prone to confounding, reverse causation and various biases and have generated findings that have proved to be unreliable indicators of the causal effects of modifiable exposures on disease outcomes. Mendelian randomization (MR) is a method that utilizes gene...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Davey Smith, George, Hemani, Gibran
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170722/
https://ncbi.nlm.nih.gov/pubmed/25064373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu328
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