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Mendelian randomization: genetic anchors for causal inference in epidemiological studies
Observational epidemiological studies are prone to confounding, reverse causation and various biases and have generated findings that have proved to be unreliable indicators of the causal effects of modifiable exposures on disease outcomes. Mendelian randomization (MR) is a method that utilizes gene...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4170722/ https://ncbi.nlm.nih.gov/pubmed/25064373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu328 |
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