Loading...
Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway
Usp5 is a deubiquitinase (DUB) previously shown to regulate unanchored polyubiquitin (Ub) chains, p53 transcriptional activity and double-strand DNA repair. In BRAF mutant melanoma cells, Usp5 activity was suppressed by BRAF inhibitor (vemurafenib) in sensitive but not in acquired or intrinsically r...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2014
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4170643/ https://ncbi.nlm.nih.gov/pubmed/24980819 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|